BioMed Research International / 2017 / Article / Fig 6

Research Article

Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ETB Receptors and Superoxide Anion

Figure 6

Effect of the SOD mimic Tempol on ET-1-induced contraction in endothelium-intact (E+) contralateral carotid rings removed from operated rats at the sixteenth day after the surgery and in E+ age-matched rats control carotid rings. (a) Cumulative concentration-response curves for ET-1 in carotid rings pretreated or not with Tempol. (b) max values from ET-1-induced contraction in carotid rings pretreated or not with Tempol. Significant difference () from E+ nonpretreated control carotid rings () or E+ nonpretreated contralateral carotid rings (#). One-way ANOVA; Bonferroni post hoc test.

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