Antimicrobial Natural Product Berberine Is Efficacious for the Treatment of Atrial Fibrillation

Table 3

Echocardiographic parameter improvement over time.

Group	Parameter	Before treatment (baseline)	After treatment
			1 month	3 months	6 months	12 months
Berberine	E/A
Amiodarone	E/A
Significance		NS	NS	NS	NS	NS
Berberine	LAD (mm)
Amiodarone	LAD (mm)
Significance		NS	NS	NS	NS	NS

Notes. baseline versus 6 months or 12 months; baseline versus 12 months; E/A, ratio of the early to late ventricular filling velocities; LAD, left atrial diameter; NS, nonsignificant difference between two groups.