MicroRNA-16-5p Inhibits Osteoclastogenesis in Giant Cell Tumor of Bone

Figure 4

Immunostaining of F-actin in RANKL-induced BMMs osteoclastogenesis treated with miR-16-5p inhibitor or mimics. (a) Immunostaining of F-actin in RANKL-induced BMMs osteoclastogenesis treated with or without miR-16-5p mimics. (b) Immunostaining of F-actin in RANKL-induced BMMs osteoclastogenesis treated with or without miR-16-5p inhibitor. Arrows point towards the F-actin ring. Mimic represents the agomir for miR-16-5p, inhibitor represents the antagomir for miR-16-5p, mimic control represents the negative control for miR-16-5p mimic, and inhibitor control represents the negative control for miR-16-5p inhibitor. Scale bar represents 10 μm. The original image magnification is 40x and the experiments were performed concomitantly.

(a)

(b)