Colonic Transit Time and Gut Peptides in Adult Patients with Slow and Normal Colonic Transit Constipation

Table 4

AUC of gut peptides release in healthy controls and constipated patients categorized according to the time of colonic transit.

	HC; (20)	NTC; (31)	STC; (20)
Neurotensin	(1320.0–2152.0)	(982.3–1373.0)	(654.0–1532.0)	0.0128
Motilin	(731.8–1252.0)	(169.3–1913.0)	(81.75–183.0)	0.0093
CRF	(265.9–317.2)	(235.9–549.9)	(229.0–407.7)	ns
Somatostatin	(141.0–213.1)	(76.83–213.8)	(103.5–255.2)	ns

Data expressed as median and the 25th–75th interquartile range and analysed by Kruskal-Wallis ANOVA with Dunn’s multiple comparison test. Values not sharing a common superscript differ significantly. HC: healthy controls; NTC: normal transit constipation; STC: slow transit constipation.