In the article titled “Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-B” [1], the cell line HEp-2 used in the study had been reported to be contaminated by HeLa, a cervical cancer cell line. Therefore, the study can only prove that the compound CA15 has antitumor effects, not antihuman laryngeal carcinoma.