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BioMed Research International
Volume 2017 (2017), Article ID 3459468, 7 pages
Review Article

Could Early Surgery Get Beneficial in Adult Patients with Active Native Infective Endocarditis? A Meta-Analysis

1Department of Cardiovascular Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China
2Department of Public Health, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China

Correspondence should be addressed to Huaien Bu and Minxin Wei

Received 10 December 2016; Revised 22 January 2017; Accepted 26 January 2017; Published 23 February 2017

Academic Editor: Paola Di Carlo

Copyright © 2017 Liqun Jia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


After a thorough search through the database as PubMed database and Embase database, the clinical experimental articles have been selected out on the effects of early surgery on the treatment of active native infective endocarditis. The quality of the trials included in this study was assessed by researcher according to the Cochrane Handbook for Systematic Reviews of Interventions, version 5.1.0. A meta-analysis was carried out in terms of clinical efficacy criteria by RevMan 5.3 software. Based on the results, we cautiously conclude that early surgery used for active native infective endocarditis could reduce in-hospital mortality, follow-up mortality, and IE-related mortality.