Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Units
Table 3
Multivariate Cox proportional regression of ICU delirium in sequential sedation patients.
Risk factors
RR
95% CL
Age (≥51)
2.432
1.316–4.494
0.005
Regular smoking
2.366
1.277–4.382
0.006
SOFA score (≥14)
2.022
1.076–3.798
0.029
The first dose of fentanyl (μg/kg/d)
0.992
0.951–1.035
0.772
The maintenance dose of midazolam (mg/kg/d)
1.052
1.000–1.107
0.049
The maintenance dose of fentanyl (μg/kg/d)
1.045
1.019–1.072
0.001
Sequential sedatives
Midazolam (group M-M)
1.000
Ref.
Propofol (group M-P)
0.706
0.364–1.369
0.303
Dexmedetomidine (group M-D)
0.448
0.209–0.963
0.040
Patients at ICU admission (before meeting the sequential criteria). When patients met the sequential criteria. After patients met the sequential criteria for extubation. .