Research Article

Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Units

Table 3

Multivariate Cox proportional regression of ICU delirium in sequential sedation patients.

Risk factorsRR95% CL

Age (≥51)2.4321.316–4.4940.005
Regular smoking2.3661.277–4.3820.006
SOFA score (≥14)2.0221.076–3.7980.029
The first dose of fentanyl (μg/kg/d)0.9920.951–1.0350.772
The maintenance dose of midazolam (mg/kg/d)1.0521.000–1.1070.049
The maintenance dose of fentanyl (μg/kg/d)1.0451.019–1.0720.001
Sequential sedatives
 Midazolam (group M-M)1.000Ref.
 Propofol (group M-P)0.7060.364–1.3690.303
 Dexmedetomidine (group M-D)0.4480.209–0.9630.040

Patients at ICU admission (before meeting the sequential criteria). When patients met the sequential criteria. After patients met the sequential criteria for extubation. .