In Vivo Studies on the Influence of Bacteriophage Preparations on the Autoimmune Inflammatory Process
Table 2
Influence of MS-1 staphylococcal phage mixture on weight and cell number of thymus, spleen, and mesenteric lymph nodes 21 days after ending of its therapeutic application in CIA model in mice.
Parameter
Control
Bacterial sonicate
MS-1 (lysate)
Mean
±SE
Mean
±SE
Mean
±SE
Total body weight (g)
10
15.1
±0.3
10
15.7
±0.5
10
14.6
±0.2
Weight of thymus (mg)
10
21.0
±1.3
10
22.4
±1.9
10
21.7
±1.2
Weight factor of thymus (×10−3)
10
1.4
±0.1
10
1.4
±0.1
10
1.5
±0.1
Number of thymocytes (×103/mm3)
10
282.0
±19.0
10
294.0
±23.3
10
292.0
±22.5
Weight of spleen (mg)
10
82.3
±1.6
10
86.4
±4.1
10
74.8
±4.9
Weight factor of spleen (×10−3)
10
5.5
±0.1
10
5.5
±0.2
10
5.1
±0.3
Number of splenocytes (×103/mm3)
10
592.0
±38.1
10
682.0
±45.0
10
776.0
±
Weight of mesenteric lymph nodes (mg)
10
29.3
±1.9
10
33.7
±2.9
10
26.6
±1.1
Weight factor of mesenteric lymph nodes (×10−3)
10
1.9
±0.1
10
2.1
±0.1
10
1.8
±0.1
Number of mesenteric lymph node cells (×103/mm3)
10
314.0
±22.3
10
268.0
±20.0
10
332.0
±19.6
when compared to control group (one-way ANOVA, post hoc Scheffe’s test).
