Research Article

Chemopreventive Potential of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside on the Formation of Aberrant Crypt Foci in Azoxymethane-Induced Colorectal Cancer in Rats

Table 3

Effects of THSG on AOM-induced ACF formation in rats.

GroupACF number
TotalInhibition (%)

ND (normal)00
AOM 15 mg/kg105 ± 1.540
AOM + THSG (30 mg/kg)89 ± 91.6
AOM + THSG (150 mg/kg)50 ± 3.4746.5
AOM + THSG (250 mg/kg)45 ± 1.2353.8

F344 rats were treated orally with different doses of THSG (30, 150, or 250 mg/kg) for 6 weeks. Data are expressed as means ± SD (). .