Red Cell Storage Duration Does Not Affect Outcome after Massive Blood Transfusion in Trauma and Nontrauma Patients: A Retrospective Analysis of 305 Patients

Table 1

Summary of baseline patient characteristics by quartiles of patient-specific mean storage duration of transfused red blood cells. Statistics reported as a percentage, mean ± standard deviation, or median [first quartile, third quartile]. Medians and quartiles are reported when the sample skewness coefficient is >0.9 in absolute value.

Factor	Level	First quartile; (8.0–17.7 days)	Second quartile; (17.7–21.6 days)	Third quartile; (21.6–26.6 days)	Fourth quartile; (26.6–36.6 days)	Percent missing
Year of admission	2006	16	8	5	7	0.7
	2007	13	11	11	5
	2008	31	26	27	13
	2009	9	17	23	41
	2010	16	16	17	16
	2011	16	22	17	17
Age		41 ± 18	45 ± 19	48 ± 18	47 ± 18
Female sex		32	33	28	29
Body mass index (kg/m^2)		26	26	26	25	36.7
Patient blood type	A−	8	11	12	7	0.7
	A+	19	30	33	37
	AB+	0	4	3	7
	B−	1	3	4	1
	B+	8	7	8	12
	O−	13	3	12	4
	O+	51	43	29	33
Type of surgery	Trauma	74	73	70	64	0.7
	Cancer	10	7	11	12
	General	6	9	11	12
	Vascular	4	9	5	7
	Gynecological	4	0	4	3
	Orthopedic	1	1	0	3
Heart disease		13	20	17	18
Pulmonary disease		14	11	7	8
Renal disease		0	5	1	1
Hypertension		26	39	41	37
Diabetes mellitus		13	4	16	12
Carcinoma		10	16	12	16
Liver disease		9	16	12	13
Tobacco use		29	29	21	24
Alcohol use		12	11	11	8
Illicit drug use		9	7	5	8
Initial heart rate (beats per minute)		107 ± 35	105 ± 37	102 ± 35	103 ± 32	1.3
Initial systolic blood pressure (mmHg)		108	100	101	111	0.7
Initial temperature (°C)		36	36	36	36	14.1
ED crystalloids (L)		2.6	2.0	1.5	2.0	32.1
Length of surgery (min)		146	140	141	140	6.9
Total number of units transfused		23	23	22	18
Minimum RBC storage duration		8 ± 3	11 ± 4	14 ± 5	19 ± 7
Maximum RBC storage duration		33	37	37	39
Initial laboratory values
Hemoglobin (g/dL)		10	11	11	10	4.3
Blood pH		7.2	7.2	7.2	7.2	2.3
Platelet count (k/mcL)		190	180	187	184	2.3
International normalized ratio		1.5	1.5	1.5	1.4	4.9
Activated prothrombin time (s)		16	15	15	15	5.2
Activated partial thromboplastin time (s)		37	35	40	33	4.9
Subset of trauma patients						—
Blunt injury		65	65	64	58
Penetrating injury		25	25	32	27
Other type of injury		11	9	4	15
Injury severity score		30 ± 10	29 ± 14	28 ± 13	27 ± 11	2.8
Glasgow coma score		10 ± 5	9 ± 6	10 ± 5	10 ± 5