First-Line Helicobacter pylori Eradication in Patients with Chronic Kidney Diseases in Taiwan

Table 4

Univariate analysis of the clinical factors influencing the efficacy of H. pylori eradication.

Principle parameter		CKD ()		value	Non-CKD ()		value
		Case number	Eradication rate (%)		Case number	Eradication rate (%)
Age	≥60 years	90/107	84.1	0.376	216/309	69.9	0.397
	<60 years	21/23	91.3		277/319	86.8
Sex	Female	66/77	85.7	0.898	286/325	88.0	0.084
	Male	45/53	84.9		252/303	83.2
Smoking	(−)	98/116	84.5	0.402	460/534	86.1	0.420
	(+)	13/14	92.9		78/94	83.0
Alcohol consumption	(−)	98/116	84.5	0.402	455/527	86.3	0.274
	(−)	13/14	92.9		83/101	82.2
Previous history of peptic ulcer	(−)	98/116	84.5	0.871	448/522	85.8	0.806
	(+)	13/14	92.9		90/106	84.9
Laboratory data
Na (mEq/L)	≥130	44/53	83.0	0.524	285/327	87.2	0.348
	<130	2/2	100		6/6	100
K (mEq/L)	≥5	10/11	90.9	0.616	6/6	100	0.337
	<5	46/54	85.2		312/360	86.7
Ca (mEq/L)	≥8	25/29	86.2	0.574	176/195	90.3	0.743
	<8	2/2	100		1/1	100
Albumin (g/dl)	≥3.5	29/34	85.3	0.679	194/218	89.0	0.321
	<3.5	1/1	100		8/8	100
BUN (mg/dl)	≥20	37/46	76.1	0.102	29/32	90.6	0.552
	<20	21/22	95.4		253/291	86.9
GFR (ml/min/1.73 m^2)	≥30	82/97	84.5	0.639	538/628	85.7	—
	<30	29/33	87.9		0
Cholesterol (mg/dl)	≥200	6/6	100	0.237	97/110	88.2	0.776
	<200	29/36	80.6		175/201	87.1
Triglyceride (mg/dl)	≥150	14/17	82.4	0.687	76/85	89.4	0.419
	<150	20/23	87.0		183/213	85.9
Hemoglobin (g/dL)	≥10	67/79	84.8	0.922	408/473	86.3	0.745
	<10	21/25	84.0		30/34	88.2

CKD: chronic kidney disease, BUN: blood urea nitrogen, GFR: glomerular filtration rate, Na: sodium, K: potassium, Cl: chloride, and Ca: calcium.