Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2017, Article ID 3796359, 10 pages
https://doi.org/10.1155/2017/3796359
Research Article

Association Study of Gut Flora in Coronary Heart Disease through High-Throughput Sequencing

1Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China
2School of Medical Science and Laboratory Medicine, Jiangsu University, Jiangsu 212013, China

Correspondence should be addressed to Xiuguo Hua; nc.ude.utjs@gxh

Received 21 November 2016; Revised 22 February 2017; Accepted 15 March 2017; Published 9 April 2017

Academic Editor: Pratik Banerjee

Copyright © 2017 Li Cui et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Sommer and F. Bäckhed, “The gut microbiota-masters of host development and physiology,” Nature Reviews Microbiology, vol. 11, no. 4, pp. 227–238, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. I. Sekirov, S. L. Russell, L. Caetano M Antunes, and B. B. Finlay, “Gut microbiota in health and disease,” Physiological Reviews, vol. 90, no. 3, pp. 859–904, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. V. Tremaroli and F. Bäckhed, “Functional interactions between the gut microbiota and host metabolism,” Nature, vol. 489, no. 7415, pp. 242–249, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. S. F. Clarke, E. F. Murphy, O. O'Sullivan et al., “Exercise and associated dietary extremes impact on gut microbial diversity,” Gut, vol. 63, no. 12, pp. 1913–1920, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. M. A. Conlon and A. R. Bird, “The impact of diet and lifestyle on gut microbiota and human health,” Nutrients, vol. 7, no. 1, pp. 17–44, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. J. K. Goodrich, J. L. Waters, A. C. Poole et al., “Human genetics shape the gut microbiome,” Cell, vol. 159, no. 4, pp. 789–799, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. J. J. Faith, J. L. Guruge, M. Charbonneau et al., “The long-term stability of the human gut microbiota,” Science, vol. 341, no. 6141, Article ID 1237439, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. R. E. Ley, P. J. Turnbaugh, S. Klein, and J. I. Gordon, “Microbial ecology: human gut microbes associated with obesity,” Nature, vol. 444, no. 7122, pp. 1022–1023, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. T. R. Abrahamsson, H. E. Jakobsson, A. F. Andersson, B. Björkstén, L. Engstrand, and M. C. Jenmalm, “Low gut microbiota diversity in early infancy precedes asthma at school age,” Clinical and Experimental Allergy, vol. 44, no. 6, pp. 842–850, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Qin, Y. Li, Z. Cai et al., “A metagenome-wide association study of gut microbiota in type 2 diabetes,” Nature, vol. 490, no. 7418, pp. 55–60, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. J. U. Scher, C. Ubeda, A. Artacho et al., “Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease,” Arthritis and Rheumatology, vol. 67, no. 1, pp. 128–139, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. W. H. W. Tang, Z. Wang, B. S. Levison et al., “Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk,” The New England Journal of Medicine, vol. 368, no. 17, pp. 1575–1584, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. E. Org, M. Mehrabian, and A. J. Lusis, “Unraveling the environmental and genetic interactions in atherosclerosis: central role of the gut microbiota,” Atherosclerosis, vol. 241, no. 2, pp. 387–399, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. Z. Wang, E. Klipfell, B. J. Bennett et al., “Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease,” Nature, vol. 472, no. 7341, pp. 57–63, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. W. H. W. Tang and S. L. Hazen, “The contributory role of gut microbiota in cardiovascular disease,” Journal of Clinical Investigation, vol. 124, no. 10, pp. 4204–4211, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. R. A. Koeth, Z. Wang, B. S. Levison et al., “Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis,” Nature Medicine, vol. 19, no. 5, pp. 576–585, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Emoto, T. Yamashita, N. Sasaki et al., “Analysis of gut microbiota in coronary artery disease patients: a possible link between gut microbiota and coronary artery disease,” Journal of Atherosclerosis and Thrombosis, vol. 23, no. 8, pp. 908–921, 2016. View at Publisher · View at Google Scholar · View at Scopus
  18. S.-F. Fu, F. Wang, X.-S. Shi, and R.-B. Guo, “Impacts of microaeration on the anaerobic digestion of corn straw and the microbial community structure,” Chemical Engineering Journal, vol. 287, pp. 523–528, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. F. Shanahan, “Probiotics in perspective,” Gastroenterology, vol. 139, no. 6, pp. 1808–1812, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. D.-W. Kang, J. G. Park, Z. E. Ilhan et al., “Reduced incidence of Prevotella and other fermenters in intestinal microflora of autistic children,” PLoS ONE, vol. 8, no. 7, Article ID e68322, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. S. J. Ott, M. Musfeldt, D. F. Wenderoth et al., “Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease,” Gut, vol. 53, no. 5, pp. 685–693, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Y. Chang, D. A. Antonopoulos, A. Kalra et al., “Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea,” Journal of Infectious Diseases, vol. 197, no. 3, pp. 435–438, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. M. J. Claesson, I. B. Jeffery, S. Conde et al., “Gut microbiota composition correlates with diet and health in the elderly,” Nature, vol. 488, no. 7410, pp. 178–184, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. S. K. Mazmanian, J. L. Round, and D. L. Kasper, “A microbial symbiosis factor prevents intestinal inflammatory disease,” Nature, vol. 453, no. 7195, pp. 620–625, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. G. D. Wu, J. Chen, C. Hoffmann et al., “Linking long-term dietary patterns with gut microbial enterotypes,” Science, vol. 334, no. 6052, pp. 105–108, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. J. Xu, M. A. Mahowald, R. E. Ley et al., “Evolution of symbiotic bacteria in the distal human intestine,” PLoS Biology, vol. 5, no. 7, article e156, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. E. Sánchez, E. Donat, C. Ribes-Koninckx, M. Calabuig, and Y. Sanz, “Intestinal Bacteroides species associated with coeliac disease,” Journal of Clinical Pathology, vol. 63, no. 12, pp. 1105–1111, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. J. M. Clarke, D. L. Topping, C. T. Christophersen et al., “Butyrate esterified to starch is released in the human gastrointestinal tract,” The American Journal of Clinical Nutrition, vol. 94, no. 5, pp. 1276–1283, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. P. Poirier, T. D. Giles, G. A. Bray et al., “Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on obesity and heart disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism,” Circulation, vol. 113, no. 6, pp. 898–918, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. J.-P. Furet, L.-C. Kong, J. Tap et al., “Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers,” Diabetes, vol. 59, no. 12, pp. 3049–3057, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Amar, C. Lange, G. Payros et al., “Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: the D.E.S.I.R. study,” PLoS ONE, vol. 8, no. 1, Article ID e54461, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. V. Dinakaran, A. Rathinavel, M. Pushpanathan, R. Sivakumar, P. Gunasekaran, and J. Rajendhran, “Elevated levels of circulating DNA in cardiovascular disease patients: metagenomic profiling of microbiome in the circulation,” PLoS ONE, vol. 9, no. 8, Article ID e105221, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. W. E. C. Moore and L. V. H. Moore, “The bacteria of periodontal diseases,” Periodontology 2000, vol. 5, no. 1, pp. 66–77, 1994. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Genco, S. Offenbacher, and J. Beck, “Periodontal disease and cardiovascular disease: epidemiology and possible mechanisms,” The Journal of the American Dental Association, vol. 133, pp. 14S–22S, 2002. View at Google Scholar · View at Scopus
  35. K. Nakano, H. Nemoto, R. Nomura et al., “Detection of oral bacteria in cardiovascular specimens,” Oral Microbiology and Immunology, vol. 24, no. 1, pp. 64–68, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. A. Cotillard, S. P. Kennedy, L. C. Kong et al., “Dietary intervention impact on gut microbial gene richness,” Nature, vol. 500, no. 7464, pp. 585–588, 2013. View at Publisher · View at Google Scholar · View at Scopus