Research Article

Tumor Burden and Intraosseous Metabolic Activity as Predictors of Bone Marrow Failure during Radioisotope Therapy in Metastasized Prostate Cancer Patients

Table 3

Results of multivariate analysis for grade III/IV hematologic toxicity.

Dependent variableDegrees of freedom value value

Age12,555NS
Weight11,978NS
PSA level13,637NS
Superscan10,33NS
counts19,3460,016
Axial counts10,134NS
Appendicular counts15,3180,045
mean counts11,374NS
Axial mean counts10,708NS
Appendicular mean counts12,933NS
INV%19,8810,014
INV% (axial skeleton)11,509NS
INV% (appendicular skeleton)112,3660,008
Appendicular invasion (INV% > median)1160,004