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BioMed Research International
Volume 2017, Article ID 3909657, 13 pages
https://doi.org/10.1155/2017/3909657
Research Article

Novel Sequential Screening and Enhanced Production of Fibrinolytic Enzyme by Bacillus sp. IND12 Using Response Surface Methodology in Solid-State Fermentation

1Centre for Marine Science and Technology, Manonmaniam Sundaranar University, Rajakkamangalam, Kanyakumari District, Tamil Nadu 629 502, India
2Kanyakumari Field Centre, Central Marine Fisheries Research Institute, Kanyakumari, Tamil Nadu 629702, India
3Department of Biotechnology, Kalasalingam University, Srivilliputtur, Virudhunagar, Tamil Nadu 626126, India
4Department of Botany and Microbiology, Addiriyah Chair for Environmental Studies, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia
5Department of Medical Education and Medical Humanities, School of Medicine, Kyung Hee University, Seoul, Republic of Korea
6Department of Medicinal Crop Research, RDA, Eumseong, Chungbuk 369-873, Republic of Korea

Correspondence should be addressed to Ponnuswamy Vijayaraghavan; moc.liamg@semyznev and Mariadhas Valan Arasu; moc.liamg@usaranalavm

Received 8 August 2016; Revised 30 November 2016; Accepted 13 December 2016; Published 22 February 2017

Academic Editor: Denise Freire

Copyright © 2017 Ponnuswamy Vijayaraghavan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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