Association between Single Nucleotide Polymorphisms in Vitamin D Receptor Gene Polymorphisms and Permanent Tooth Caries Susceptibility to Permanent Tooth Caries in Chinese Adolescent

Table 4

Haplotype analysis and permutation tests.

(a)

Haplotype	Freq.	Case, control ratio counts	Case, control frequencies		value
TCGC	0.309	132.7 : 267.3, 114.7 : 285.3	0.332, 0.287	1.901	0.168
TCGT	0.25	80.3 : 319.7, 119.5 : 280.5	0.201, 0.299	10.259	0.0014
TAGC	0.197	89.7 : 310.3, 67.9 : 332.1	0.224, 0.170	3.758	0.0525
TAGT	0.088	35.0 : 365.0, 35.4 : 364.6	0.087, 0.088	0.003	0.9596
TCAT	0.05	21.9 : 378.1, 18.4 : 381.6	0.055, 0.046	0.312	0.5764
CAGT	0.03	12.1 : 387.9, 12.1 : 387.9	0.030, 0.030	0	0.9992
CCGC	0.018	7.6 : 392.4, 6.5 : 393.5	0.019, 0.016	0.088	0.7669
CCGT	0.017	4.1 : 395.9, 9.2 : 390.8	0.010, 0.023	1.979	0.1595
TAAC	0.013	9.4 : 390.6, 1.2 : 398.8	0.023, 0.003	6.391	0.0115

(b) #999 permutations performed

Name		Permutation value
TCGT	10.259	0.016
Fok I (rs10735810)	8.544	0.026
TAAC	6.391	0.0581
TAGC	3.758	0.3033
Apa I (rs7975232)	3.175	0.4765
Taq I (rs731236)	2.612	0.6056
CCGT	1.979	0.7217
TCGC	1.901	0.7598
Bsm I (rs1544410)	0.407	0.998
TCAT	0.312	0.998
TAGT	0.003	1
CAGT	0	1
CCGC	0.088	1