Research Article

Effect of R119G Mutation on Human P5CR1 Dynamic Property and Enzymatic Activity

Figure 5

(a) Superimposed 3D structures of WT (blue) and R119H mutant (pale green) P5CR. (b) Changes in the protein stability upon R119H mutation predicted by Foldx. values are changes in the protein unfolding free energy after mutation. ΔΔG < 0: increased stability; ΔΔG > 0: decreased stability.
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