Effects of FMO3 Polymorphisms on Pharmacokinetics of Sulindac in Chinese Healthy Male Volunteers

Figure 4

The mean plasma concentration-time curves of sulindac (a), sulindac sulfide (b), and sulindac sulfone (c) in FMO3 HHDD homozygotes () and FMO3 hhdd homozygotes () after a single oral dose of 200 mg sulindac tablets.

(a)

(b)

(c)