Expression of Cancer Stem Cell Marker CD44 and Its Polymorphisms in Patients with Chronic Gastritis, Precancerous Gastric Lesion, and Gastric Cancer: A Cross-Sectional Multicenter Study in Thailand

Table 2

The distribution of the gastric mucosal pathology related to expression of CD44 and polymorphisms.

Polymorphism of gastric mucosal pathology	Expression of CD44 protein (%)		OR (95% CI)	value
	Negative	Positive
Precancerous
(i) AA	10.71	7.14	0.68 (0.47–0.96)	0.693
(ii) AG	35.71	14.28	0.91 (0.87–1.86)	0.058
(iii) GG	28.57	-	-	-
Gastric cancer
(i) AA	-	2.56	-	-
(ii) AG	7.69	35.89	5.67 (1.54–7.23)	0.02
(iii) GG	10.25	43.58	8.32 (2.94–11.42)	0.01
Gastric cancer
(i) AG	7.69	35.89	3.28 (2.47–5.63)	0.03
(ii) GG	10.25	43.58	4.14 (1.84–7.32)	0.04

Cox regression model analysis used to analyze the data. Multivariate Cox proportional hazards regression model analysis was used to analyze the data. OR, odds ratio; CI, confidence interval. Significance is set at < 0.05.