Pharmacokinetics, Tissue Distribution, and Metabolism Study of Icariin in Rat

Figure 3

Representative MRM chromatograms of blank plasma (a-1), blank liver (a-2), blank plasma spiked with IS (b-1), blank liver spiked with IS (b-2), blank plasma spiked with icariin at LOQ (c-1), blank liver spiked with icariin at LOQ (d-1), rat plasma sample obtained at 0.5 h after administration (c-2), and rat liver sample obtained at 0.5 h after administration (d-2).