Age-Adjusted D-Dimer in the Prediction of Pulmonary Embolism: Does a Normal Age-Adjusted D-Dimer Rule Out PE?
Table 2
Predictive power of Wells score and its elements.
Data-defined
Odds ratio† (95% CI)
value†
Sensitivity†
Specificity†
Sensitivity + specificity
Wells score (continuous)
≥5
4.07 (2.76, 6.05)
<0.001
0.61
0.72
1.33
Wells Score > 4
—
3.11 (2.08, 4.75)
<0.001
0.71
0.55
1.27
HR > 100
—
1.21 (0.83, 1.77)
0.335
0.56
0.48
1.05
Stasis (+ versus −)
—
1.21 (0.82, 1.78)
0.332
0.39
0.66
1.04
Signs of DVT (+ versus −)
—
4.41 (2.84, 6.80)
<0.001
0.34
0.89
1.24
Hemoptysis (+ versus −)
—
1.54 (0.56, 3.61)
0.358
0.05
0.97
1.02
Cancer (+ versus −)
—
1.45 (0.97, 2.2)
0.069
0.35
0.73
1.08
Previous DVT/PE (+ versus −)
—
2.05 (1.27, 3.23)
0.003
0.23
0.87
1.10
at which probability of PE predicted by logistic regression model equals or first exceeds observed frequency of PE. data-defined cutoff, where applicable.
