Review Article
CD147 as a Novel Prognostic Biomarker for Hepatocellular Carcinoma: A Meta-Analysis
Table 3
Results of subgroups analysis.
| | OS | DFS/RFS | Number | HR (95% CI) | | (%) | | Model | Number | HR (95% CI) | | (%) | | Model |
| Total | 4 | | | | | | 4 | | | | | | Univariate/Multivariate | | | | | | | | | | | | | Multivariate | 1 | 0.5 (0.26, 0.96) | | | 0.04 | | 2 | 7.72 (2,86, 20.86) | 0.84 | 0 | <0.0001 | Fixed | Univariate | 3 | 2.21 (1.44, 3.38) | 0.15 | 48 | 0.0003 | Fixed | 2 | 2.08 (1.01, 4.26) | 0.75 | 0 | 0.05 | Fixed | Follow-up time | | | | | | | | | | | | | More than 5 years | 2 | 1.75 (0.57, 5.34) | 0.1 | 63 | 0.33 | Random | 2 | 2.10 (0.84, 5.23) | 0.46 | 0 | 0.11 | Fixed | Less than 5 years | 1 | 0.50 (0.26, 0.96) | | | 0.04 | | 2 | 4.40 (2,07, 9.36) | 0.11 | 60 | 0.0001 | Fixed | Liver transplantation | | | | | | | | | | | | | Yes | 0 | | | | | | 2 | 4.40 (2.07, 9.36) | 0.11 | 60 | 0.0001 | Fixed | No | 4 | 1.35 (0.56, 3.29) | 0.0006 | 83 | 0.51 | Random | 2 | 2.10 (0.84, 5.23) | 0.46 | 0 | 0.11 | Fixed | Cut-off value | | | | | | | | | | | | | More than 10% of cells stained | 1 | 2.80 (1.41, 5.56) | | | 0.03 | | 2 | 3.81 (0.92, 15.76) | 0.05 | 75 | 0.07 | Random | Less than 10% of cells stained | 1 | 0.50 (0.26, 0.96) | | | 0.04 | | 2 | 2.64 (0.96, 7.25) | 0.56 | 0 | 0.06 | Fixed |
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means the heterogeneity of value.
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