Research Article

Obesity Induces Artery-Specific Alterations: Evaluation of Vascular Function and Inflammatory and Smooth Muscle Phenotypic Markers

Table 2

Body composition and serum metabolic and inflammatory markers of C57BL/6 mice after 16 weeks of feeding with control (control mice) and high-fat diet (obese mice).

Control miceObese mice

Gain of body weight (g)9.5 ± 0.3
Retroperitoneal fat/body weight (mg/g)3.4 ± 0.5
Periepididymal fat/body weight (mg/g)10.1 ± 1.1
Triglycerides (mg/dl)47.1 ± 4.238.3 ± 5.3
Total cholesterol (mg/dl)87.4 ± 4.5
HDL (mg/dl)54.7 ± 2.6
LDL (mg/dl)25.1 ± 2.4
Glucose (mg/dl)127.0 ± 2.1
Insulin (pmol/l)25.6 ± 3.6
TNF-α (pg/ml)26.6 ± 1.7
IL-6 (pg/ml)57.5 ± 2.946.6 ± 7.3

Data are expressed as mean ± SEM. Unpaired -test: versus control mice. .