Role of Transient Receptor Potential Vanilloid 1 in Electroacupuncture Analgesia on Chronic Inflammatory Pain in Mice
Expression levels of TRPV1-associated signaling pathway in mice DRG. (a) TRPV1, pPKA, pPI3K, and pPKC. (b) pERK, pp38, pJNK, and pAkt. (c) pmTOR, pCREB, pNFκB, and Nav1.7. (d) Nav1.8, GFAP, S100B, and RAGE expression levels in tissues from Con, CIP, 2 Hz EA, sham EA, and TRPV1−/− groups (from left to right). Con: control; CIP: chronic inflammatory pain; EA: electroacupuncture; sham EA: sham electroacupuncture; KO: TRPV1 knockout mice. versus Con. versus CUP group. The western blot bands at the top show the target protein. The lower bands are internal controls (β-actin or α-tubulin).
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