The Glymphatic Hypothesis of Glaucoma: A Unifying Concept Incorporating Vascular, Biomechanical, and Biochemical Aspects of the Disease

Figure 1

Schematic depiction of our hypothesis. Cerebrospinal fluid enters the paravascular spaces in the retina along a para-arterial influx route around the central retinal artery (a), followed by a paravenous clearance efflux route around the central retinal vein (b) (Figures 1(a) and 1(b) reproduced from [9]).

(a)

(b)