Structure and Function of Trypsin-Loaded Fibrinolytic Liposomes

Figure 1

Permeation-driven lysis of fibrin and plasma clots. (solid lines) or HBS (dashed lines) was layered to the surface of fibrin (a) or plasma (b) clots; thereafter a constant hydrostatic pressure was maintained over the clots and the eluted fluid was collected in fractions of 50 μl each, in which the protein content was measured and is shown as mean ± SEM (). Red and blue colours indicate clot lysis at 45°C and 24°C, respectively.

(a)

(b)