Identification of Significant Pathways Induced by PAX5 Haploinsufficiency Based on Protein-Protein Interaction Networks and Cluster Analysis in Raji Cell Line

Figure 3

The differentially expressed genes were used to search the STRING database to predict their protein-protein interactions in pax5 mutation cells. In the network shown, the nodes are the proteins and the lines represent the predicted functional associations. The number of lines indicates the strength of the predicted functional interactions of the proteins. (a) Network of differentially expressed genes (DEGs). (b) The downregulated DEG PPI subnetwork. (c) The upregulated DEG PPI subnetwork.

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