Comparison of DNA Methylation in Schwann Cells before and after Peripheral Nerve Injury in Rats

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Biological function</td><td class="align_center">Gene number</td><td class="align_center">Partial related methylated genes</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Adhesion</td><td class="align_center">580</td><td class="align_center">Sox-2, Shh, Itpkb, Pkd1, Reln, Ptk2b, Nck2, Ass1<br/>Lphn1, Cdh9, Epdr1, Myf5, Pdpn, Has2, Fgfrl1, Fer</td></tr><tr><td class="align_left">Secretion</td><td class="align_center">553</td><td class="align_center">Lphn1, Pim3, Fst, Pim3, Pcsk6, Lax1, Sct, Sytl3<br/>Plcd1, Ykt6, Jak1, Stat2, Myc, Csf2, Lifr, Sos1</td></tr><tr><td class="align_left">Proliferation</td><td class="align_center">787</td><td class="align_center">Dixdc1, Lrp6, Edn3, Nkx2, Cyr61, Src, Sox8, Stk4<br/>Ephb1, Sstr3, Rrm2, Tcf3, Grn, Rhoa, Apc, Nox4, Strn</td></tr><tr><td class="align_left">Neuronal regeneration</td><td class="align_center">473</td><td class="align_center">Bhlhb9, Cckar, Fzd2, Thy1, Pbx3, Otx2, Lhx8, Btg2<br/>Klhl1, Dlg2, Pak1, Wnt3, Mif, Tctn1, Evl, Ext1, Als2</td></tr><tr><td class="align_left">Axonal regeneration</td><td class="align_center">215</td><td class="align_center">Ifrd1, c-Jun, Bcl2, Tnn, Mbp, Slit3, Ist1, Drgx, Thy1<br/>Unc5c, Ntrk2, Isl1, Ptk2, Dscam, Atl1, Dnm2, Cxcl12</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Five aspects of genes related to repairment of peripheral nerve injury.

BioMed Research International

tab6

Table 6

Table 6: Comparison of DNA Methylation in Schwann Cells before and after Peripheral Nerve Injury in Rats 