Research Article

Prognostic Significance of Blood Transfusion in Newly Diagnosed Multiple Myeloma Patients without Autologous Hematopoietic Stem Cell Transplantation

Table 1

Demographic and clinicopathological characteristics of MM patients before treatment.

CharacteristicTransfused
() (%)
Nontransfused
() (%)

Age≥6040 (58.8)60 (53.1)0.537
<6028 (41.2)53 (46.9)
GenderMale38 (55.9)76 (67.3)0.153
Female30 (44.1)37 (32.7)
Ig isotypeIgG40 (58.8)57 (50.4)0.208
IgA18 (26.5)29 (25.7)
Light chain10 (14.7)21 (18.6)
Others0 (0)6 (5.3)
ISS stagingI5 (7.4)26 (23.0)0.006
II31 (45.6)55 (48.7)
III32 (47.0)32 (28.3)
ECOG0-152 (76.5)101 (89.4)0.020
2–416 (23.5)12 (10.6)
Plt (×109/L)≥10052 (76.5)104 (92.0)0.003
<10016 (23.5)9 (8.0)
Hb (g/L)≥1006 (8.8)49 (43.4)0.000
<10062 (91.2)64 (56.6)
Scr (μmol/L)≥17724 (35.3)15 (13.3)0.001
<17744 (64.7)98 (86.7)
Serum Alb (g/L)≥3513 (19.1)36 (31.9)0.062
<3555 (80.9)77 (68.1)
Serum -MG (μmol/L)≥5.532 (47.0)32 (28.3)0.011
<5.536 (53.0)81 (71.7)
Serum LDH (IU/L)≥24514 (20.6)14 (12.4)0.140
<24554 (79.4)99 (87.6)
Serum Ca (mmol/L)
≥2.7511 (16.2)10 (8.8)0.136
<2.7557 (83.8)103 (91.2)
BortezomibYes51 (75.0)60 (53.1)0.003
No17 (25.0)53 (46.9)
ThalidomideYes54 (79.4)90 (79.6)0.970
No14 (20.6)23 (20.4)

Ig: immunoglobulin; ISS: International Staging System; ECOG: Eastern Cooperative Oncology Group; Plt: platelet; Hb: hemoglobin; Scr: serum creatinine; Alb: albumin; -MG: -microglobulin; LDH: lactate dehydrogenase; Ca: calcium.