Optimization of Catheter Based rtPA Thrombolysis in a Novel In Vitro Clot Model for Intracerebral Hemorrhage

Figure 6

Effectiveness of 1 mg rtPA in different old clots: 90 min (red), 24 h (blue), and 48 h (green): the graph shows the relative weight in percent (-axis) after 1 till 4 treatment cycles (-axis) (). On top axis the time course shows cycles of 25 min, consisting of 15 min of rtPA-exposure and 10 min drainage period. indicates the significant weight difference of 90 min old clots compared to 24 h () and 48 h old clots () during the first treatment. indicates the significant weight difference of the 90 min old clots compared to 24 h old clots () during the second treatment.