Review Article
Choroidal Thickness in Women with Uncomplicated Pregnancy: Literature Review
Table 1
Characteristics of included studies.
| | Studies | Study groups with the numbers of included women | Age (yr)
Mean ± SD
Normal pregnant women | Age (yr)
Mean ± SD
Control group | Gestational age (wk)+ mean ± SD | EDI-OCT | Type of measurement | Measured areas | SFCT (um)
Mean ± SD | Normal pregnant
women
() | Normal non-pregnant
women
() | Women with Preeclampsia
() | Women after pregnancy
() | Normal pregnant
women | Control group |
| | Liu et al. | 46 | 71 | Not applicable | Not applicable | 27.87 ± 3.65 | 28.43 ± 3.15 | 28–38
(30.20 ± 1.63) | Heidelberg | Manually | SFCT,
1 mm and 3 mm nasally, temporally, superiorly, inferiorly | 344.13 ± 50.94 | 315.03 ± 60.57 |
| | Takahashi et al. | 25 | 27 | Not applicable | Not applicable | 30.4 ± 6.0 | 30.0 ± 6.3 | 27–38
(31.0 ± 3.2) | Heidelberg | Manually | SFCT,
3 mm temporally;
3 mm nasally;
3 mm superiorly;
3 mm inferiorly | 275 ± 84 | 273 ± 92 |
| | Kara et al. | 100 | 100 | Not applicable | Not applicable | 28.6 ± 6.3 | 30.5 ± 6.2 | 15–38
(27.3 ± 6.6) | Cirrus HD-OCT | Manually | SFCT | 371.1 ± 61.8 | 337.2 ± 62.4 |
| | Ulusoy et al. | 29 | 36 | Not applicable | 29 | 27.41 ± 5.48 | 28.00 ± 5.27 | 28–39
(31.97 ± 3.77) | Heidelberg | Manually | SFCT | 387.97 ± 59.91 | 320.86 ± 59.18 |
| | Dadaci et al. | 27 | 25 | Not applicable | Not applicable | 28.9 ± 5.5 | 29.2 ± 7.0 | 6–8
(6.8 ± 0.8)
32–37
(35.1 ± 1.9) | Cirrus HD-OCT | Manually | SFCT;
three locations nasal and three locations temporal to the fovea at 500 um intervals | I trimester OP
349.22 ± 82.11 μm
III trimester OP
333.56 ± 76.61 μm
I trimester OL
341.30 ± 85.22 μm
III trimester OL
326.93 ± 75.84 μm | OP-318.88–53.13
OL-310.60–51.09 |
| | Sayin et al. | 46 | 40 | 33 | Not applicable | 28.1 ± 6.2 | 30.2 ± 6.2 | 17–37
(28.0 ± 5.8) | Cirrus-HD-OCT | Manually | SFCT | 368.6 ± 67.6 | 334.8 ± 59.9 |
| | Goktas et al. | 90:
30 - I trimester
30 - II trimester
30 – III trimester | 30 | Not applicable | Not applicable | 28.5 ± 6.4
26.6 ± 4.2
26.9 ± 6.2 | 29.4 ± 2 | 7.4 ± 2.6
19.2 ± 2.9
33.1 ± 2.8 | Heidelberg | Manually | SFCT;
3 mm temporally; 3 mm nasally | I trimester
362 ± 81
II trimester
395 ± 80
III trimester
368 ± 70 | 335 ± 86 |
| | Kim et al. | 14 | 21 | 7 | Not applicable | 31.43 ± 2.88 | 30.43 ± 4.15 | 32.14 ± 2.69 | Heidelberg | Manually | SFCT | 274.23 ± 29.30 | 264.95 ± 21.03 |
| | Rothwell et al. | 12 | 12 | Not applicable | Not applicable | 32.77 ± 2.08 | 32.92 ± 3.01 | 29–35
32.4 | Heidelberg | Automatically | SFCT; + 9 subfields defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) | 319.58 ± 6.11 | 287.58 ± 43.44 |
| | Ataş et al. | 25 | 26 | 27 | Not applicable | 27.76 ± 5.21 | 29 ± 7.1 | 31.37 ± 4.9 | Heidelberg | Manually | SFCT | 387.2 ± 60.76 | 322.35 ± 63.89 |
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