Research Article

A Comparison of Fosaprepitant and Ondansetron for Preventing Postoperative Nausea and Vomiting in Moderate to High Risk Patients: A Retrospective Database Analysis

Table 2

Postoperative parameters.

NK1 group, ONS group, value

0–2 hours
 PONV34 (41%)25 (28%)0.077
 Complete response64 (78%)71 (80%)0.852
 Vomiting2 15 (17%)0.0016
 Rescue antiemetic use18130.238
0–24 hours
 PONV45 (55%)44 (49%)0.647
 Complete response58 (71%)60 (67%)0.741
 Vomiting2 25 (28%)<0.0001
 Rescue antiemetic use30260.331
0–48 hours
 PONV45 (55%)47 (53%)0.878
 Complete response58 (71%)60 (67%)0.741
 Vomiting2 26 (29%)<0.0001
 Rescue antiemetic use30290.631

Data are presented as number of patients (percentile); NK1 group, i.v. fosaprepitant; ONS group, i.v. ondansetron; PONV, postoperative nausea and vomiting. <0.05 compared to ONS group.