Sertraline Induces Toxicity and Behavioral Alterations in Planarians

Figure 2

The effect of sertraline on planarian locomotor activity. The effect of different sertraline concentrations on the spontaneous planarian movement (pLMV) was quantified following sequential incubations of 25 min (a), 24 h (b), and 24 h after sertraline withdrawal (c). Dotted line represents control levels. Data are expressed as mean ± SEM from 5 independent experiments (). indicates being significantly different from the control; indicates being significantly different from each other ().

(a)

(b)

(c)