BioMed Research International / 2017 / Article / Tab 5 / Review Article
Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems Table 5 Other EGCG nanocarriers. Note . N/A denotes “not available” data.
Particle Loading capacity (%) Loading efficiency (%) Size (nm) Administration route In vitro/in vivo results Ref. Selenium N/A N/A 29 N/A Enhanced capacity to inhibit Aβ fibrillation and promote fibril disaggregation. Protection of PC-12 against Aβ -mediated toxicity. [54 ] Transfersomes N/A 76.5 101.2 Topical Increased ability to suppress lipid peroxidation, ROS generation, and MMPs expression. Enhanced ex vivo skin permeation and deposition of EGCG across rat skin. [55 ] Peptide dendrimers (glycine, proline, lysine, and arginine) N/A N/A N/A Topical Enhanced ex vivo skin permeation and deposition of EGCG across rat skin. [56 ] Gelatin N/A 97.13 168.87 Ocular Inhibition of HUVECs proliferation and migration. Inhibition of vessel formation in a corneal neovascularization mouse model. [57 ] β -Lactoglobulin-chlorogenic acid~7.3 ~73 ~110 N/A Enhanced EGCG stability in physiological environments. Controlled release in simulated gastric and intestinal environments. [58 ]