Research Article
HIF1A (rs11549465) and AKNA (rs10817595) Gene Polymorphisms Are Associated with Primary Sjögren’s Syndrome
Table 1
Clinical and serological characteristics of PSS patients.
| | Variable | Primary Sjögren’s syndrome () |
| | Median age in years (interquartile range) | 55 (17) | | Female, (%) | 105 (95.45) | | Median disease duration in years (interquartile range) | 7.8 (10) | | Ocular symptoms, (%) | 90 (90.9) | | Oral symptoms, (%) | 103 (93.6) | | Parotid enlargement, (%) | 60 (54.6) | | Positive Schirmer-I test, (%) | 96 (87.3) | | Impaired nonstimulated whole salivary flow, (%) | 96/103 (93.2) | | Positive fluorescein staining, (%) | 53/80 (66.2) | | Positive anti-Ro/SSA antibodies, (%) | 91 (82.7) | | Positive anti-La/SSB antibodies, (%) | 53 (48.18) | | Skin vasculitis, (%) | 2 (1.8) | | Neurological involvement, (%) | 12 (10.9) | | Raynaud’s phenomenon (%) | 11 (10) | | Nonerosive arthritis, (%) | 23 (20.9) |
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