Clinical Study

Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

Table 1

Baseline characteristics and comorbidities.

Simvastatin ()Control () value

Gender (male/female)20/3622/32
Age (year)0.131
Weight (kg)0.245
Height (cm)0.094
CPB duration (min)0.464
Aorta clamping duration (min)0.296
Atrial fibrillation (persons)14120.847
Diabetes (persons)230.742
Ejection fraction EF (%)0.958
Cardiac function (NYHA class)0.704
 I34
 II1415
 III3833
 IV12
Blood lipid level
 Total cholesterol (mmol/L)0.171
 Triglyceride (mmol/L)0.056
 Low density lipoprotein (mmol/L)0.187
 High density lipoprotein (mmol/L)0.469

Data expressed as mean ± standard deviation. CPB: cardiopulmonary bypass; NYHA: New York Heart Association.