Clinical Study

Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

Table 3

Patients’ postoperative course.
(a)

GroupDuration of assisted respiration24 Hr average urine volume24 Hr total drainageDuration of
staying in ICU
EF 10 days after operation
(h)(ml/h)(ml)(h)(%)

Simvastatin group
Control group
−2.2081.761−0.994−1.1522.290
0.0300.0810.3220.2520.024

(b)

GroupTotal cholesterolTriglycerideLow-density lipoproteinHigh-density lipoprotein
(mmol/L)(mmol/L)(mmol/L)(mmol/L)

Simvastatin group
Control group
−1.057−1.876−1.224−1.906
0.2930.0630.2240.059

compared with control group. EF: ejection fraction; ICU: intensive care unit.