Hidden IgG Antibodies to the Tumor-Associated Thomsen-Friedenreich Antigen in Gastric Cancer Patients: Lectin Reactivity, Avidity, and Clinical Relevance

Figure 8

The probability of cancer patients survival in relation to anti-TF IgG level, SNA reactivity, and the avidity of TF-specific antibodies in serum and purified total IgG samples. Patients with either lower/equal (a dashed line) or higher values than median (a solid line) are compared using the Kaplan-Meier method. HR: hazard ratio with 95% confidence interval and values are shown. (a) Anti-TF IgG level in serum (stage 3); (b) anti-TF IgG level in tIgG (stage 3); (c) the SNA binding to serum TF-specific antibodies; (d) the SNA binding to anti-TF IgG in tIgG; (e) the avidity of anti-TF IgG in serum; (f) the anti-TF IgG antibody avidity in tIgG and survival.

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