Research Article

Hypofibrinolytic State in Subjects with Type 2 Diabetes Mellitus Aggravated by the Metabolic Syndrome before Clinical Manifestations of Atherothrombotic Disease

Table 2

Genotype distribution and allele frequencies of -675 4G/5G polymorphism of the PAI-1 gene in diabetic subjects with the Metabolic Syndrome and the reference group.

MetS Reference group

Genotype, (%)
 4G/4G + 4G/5G129 (60)185 (60.3)1.0
 5G/5G86 (40)122 (39.7)
 4G/4G25 (11.6)26 (8.5)0.30
 4G/5G104 (48.4)159 (51.8)
 5G/5G86 (40)122 (39.7)
Allelic frequency, (%)0.67
 4G154 (35.8)211 (34.4)
 5G276 (64.2)403 (65.6)

Categorical variables are expressed as total number and percentages. PAI-1: plasminogen activator inhibitor type-1; MetS: the Metabolic Syndrome; : test.