Genetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population

Table 3

Genotype distributions and detailed association results.

Genotype	IS ()	Control ()	OR (95% CI)		OR (95% CI)
rs7620580
AA	199	228	1.000		1.000
AG	166	122	1.559 (1.153–2.107)	0.004	1.534 (1.011–2.328)	0.045
GG	20	12	1.910 (0.911–4.004)	0.087	3.195 (1.228–8.312)	0.017
Recessive			1.598 (0.770–3.318)	0.208	2.686 (1.049–6.879)	0.039
Additive			1.490 (1.157–1.919)	0.002	1.636 (1.163–2.300)	0.005
Dominant			1.590 (1.187–2.130)	0.002	1.662 (1.110–2.487)	0.014
rs2289843
TT	101	107	1.000		1.000
TA	195	181	1.141 (0.813–1.602)	0.445	1.291 (0.809–2.059)	0.285
AA	89	74	1.274 (0.845–1.922)	0.248	1.402 (0.807–2.434)	0.231
Recessive			1.170 (0.826–1.658)	0.377	1.197 (0.748–1.914)	0.453
Additive			1.130 (0.920–1.386)	0.243	1.189 (0.903–1.566)	0.216
Dominant			1.180 (0.857–1.625)	0.311	1.326 (0.856–2.053)	0.206
rs1708303
AA	241	260	1.000		1.000
AG	132	94	1.515 (1.103–2.081)	0.010	1.610 (1.040–2.490)	0.033
GG	12	8	1.618 (0.650–4.027)	0.301	1.550 (0.484–4.969)	0.461
Recessive			1.424 (0.575–3.524)	0.445	1.338 (0.421–4.250)	0.622
Additive			1.438 (1.092–1.892)	0.010	1.476 (1.020–2.135)	0.039
Dominant			1.523 (1.119–2.073)	0.007	1.604 (1.051–2.447)	0.028

adjusted for age, SBP, DBP, FPG, TG, HDL, LDL, smoking, drinking, and BMI.