Fabrication and Evaluation of Electrospun, 3D-Bioplotted, and Combination of Electrospun/3D-Bioplotted Scaffolds for Tissue Engineering Applications

Figure 1

Fabrication of combined micro- and nanofibrous scaffold by sandwiching an electrospun layer between 3D-bioplotted layers. (a) Schematic of technical approach. (b) 3D-bioplotted scaffold with and without an electrospun layer (scale bars top = 2 mm; bottom = 500 μm). (c) Cross-sectional CAD representation of three different scaffolds created and evaluated. Top: microfibrous scaffold fabricated using 3D bioplotting technique only. Middle: nanofibrous scaffold fabricated using electrospinning only. Bottom: alternating micro- and nanosized fibers by combining 3D bioplotting and electrospinning techniques. Colors and textures for visualization purposes only.

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