Clinical Study

The Efficacy of Single-Dose versus Double-Dose Praziquantel Treatments on Schistosoma mansoni Infections: Its Implication on Undernutrition and Anaemia among Primary Schoolchildren in Two On-Shore Communities, Northwestern Tanzania

Table 3

Reinfection with S. mansoni at 5 months and 8 months after treatment stratified by sex, village, and age.

Characteristic 5 months 8 months
1 × 40 mg/kg 2 × 40 mg/kg value 1 × 40 mg/kg 2 × 40 mg/kg value
Cured at
8 weeks
Reinfected at 5 months (%)Cured at
8 weeks
Reinfected at 5 months (%)Cured at
8 weeks
Reinfected at 8 months (%)Cured at
8 weeks
Reinfected at 8 months (%)

Overall11274 (66.07)150102 (68.00)0.742121100 (82.64)148114 (77.03)0.256
Sex
 Male6043 (71.67)6945 (65.22)0.4336555 (84.62)7159 (83.10)0.810
 Female5231 (59.62)8157 (70.37)0.2015645 (80.36)7755 (71.43)0.239
Village
 Kibuyi5836 (62.07)7238 (52.78)0.2886761 (91.04)7859 (75.64)0.01
 Busanga5438 (70.37)7864 (82.05)0.1155439 (72.22)7055 (78.57)0.413
Age (years)
 6–91713 (76.47)3629 (80.56)0.7322822 (78.57)3935 (89.74)0.206
 10–125635 (62.50)7351 (69.86)0.3795345 (84.91)7556 (74.67)0.162
 13–163926 (66.67)4122 (53.66)0.2354033 (82.50)3423 (67.65)0.138

indicates statistical significance.