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BioMed Research International
Volume 2017, Article ID 7038579, 9 pages
https://doi.org/10.1155/2017/7038579
Research Article

Long Noncoding RNA PVT1 as a Novel Diagnostic Biomarker and Therapeutic Target for Melanoma

1Department of Burn and Plastic Surgery, The 253rd Hospital of PLA, Hohhot, Inner Mongolia 010051, China
2Intensive Care Unit, The 253rd Hospital of PLA, Hohhot, Inner Mongolia 010051, China
3Department of General Surgery, The 253rd Hospital of PLA, Hohhot, Inner Mongolia 010051, China

Correspondence should be addressed to Xiangjun Chen; moc.361@352_jxc

Received 26 September 2016; Revised 18 December 2016; Accepted 21 December 2016; Published 7 February 2017

Academic Editor: Junya Kuroda

Copyright © 2017 Xiangjun Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Figure 1: PVT1 (NR_003367) is the main transcription variant in melanoma tissues and cells. (a) Schematic outlining the PVT1 transcription variants from UCSC (http://genome.ucsc.edu/). We named the PVT1 variants as PVT1-1, PVT1-2, PVT1-3, PVT1-4, PVT1-5 indicating the PVT1 variants shown in this figure from above to below. PVT1-4 indicts the human PVT1 revealed in NCBI (https://www.ncbi.nlm.nih.gov/), known as NR_003367. (b) The expression levels of PVT1 transcription variants in melanoma tissues and cells were measured by qPCR. The Ct values normalized by GAPDH are shown. Data are presented as mean ± SD. n = 3.

  1. Supplementary Material