Comparison of the Protective Effects of Individual Components of Particulated trans-Sialidase (PTCTS), PTC and TS, against High Cholesterol Diet-Induced Atherosclerosis in Rabbits

Table 2

Plaque measurements of the ascending aorta from animals in each group after H&E staining. Data are expressed as mean ± SD.

	PE (mm)	PI (mm)	LP (mm^2)	LR (mm^2)	AP (mm^2)	AM (mm^2)	% Obs
CNeg	15.1 ± 1.3	12.3 ± 1.5	6.8 ± 1.6	6.8 ± 1.6	0 ± 0	5.9 ± 0.8	0 ± 0
CPos	15.1 ± 1.1	12.5 ± 1	5.9 ± 1.8	4.3 ± 1.7	2.1 ± 1.6	5.7 ± 0.4	28.6 ± 17.6
PTC	17.2 ± 1.7	14.7 ± 1.6	9.9 ± 3.1	7.3 ± 1.7	3 ± 2.6	6.7 ± 1.9	24.3 ± 11.7
TS	15.9 ± 0.6	13.2 ± 0.6	7.5 ± 2.5	5.9 ± 3	1.7 ± 1.7	6.3 ± 1.9	24.4 ± 17.7
PTCTS	17.1 ± 1.1	14.1 ± 1.3	9.7 ± 2.3	7.4 ± 2.8	2.3 ± 1.5	7.3 ± 1.1	24.5 ± 16.9

PE: external elastic lamina perimeter; PI: internal elastic lamina perimeter; AM: area of the middle layer; LP: potential lumen of the vessel, vessel lumen without the plaque; LR: real lumen of the vessel, vessel lumen with the plaque; AP: the area of atheromatous plaque; % Obs: percentage of vessel obstruction.