Review Article

Unilateral Aplasia versus Bilateral Aplasia of the Vertebral Artery: A Review of Associated Abnormalities

Table 7

Single right VA aplasia versus bilateral VA aplasia.

NumberParametersRight VABilateral VA
31 cases31 cases

(1)Incidence40.32%59.68%

(2)Gender
 Female22.58%17.74%
 Male22.58%30.64%
 Female/male/unknown gender40.32%/53.12%/6.45%

(3)Persistence of CVBA
 Unilateral persistence of CVBA80.64%59.07%
 Bilateral persistence of CVBA034.48%
 Persistence of two different CVBAs03.22%
 Persistence of determined CVBA
  PPIA16.13%54.83%
  PPHA51.61%32.25%
  PPTA6.45%9.67%
  Unusual arterial anastomoses6.45%6.45%

(4)Additional vascular variants
 Associated aplasia of other vesselsUni-Bi-Uni-Bi-Uni-Bi-
ECAs3.22%
ICA6.45%
ACA3.22%
PCoAPCoAs12.90%6.45%3.22%9.67%
BA3.22%3.22%
SA branches3.22%
 Hypoplastic left VA41.93%
 Unusual origin or side branches or termination or hypoplasia of other arteries or additional anastomoses32.25%41.93%

(5)Associated vascular pathology
 Aneurysms of definitive arteries25.80%16.13%
 Aneurysms of CVBAs3.22%3.22%
 Different cerebral pathology (except that of cerebral aneurysms)35.48%35.48%
 Noncerebral pathology9.67%3.22%

VA, vertebral artery; CVBA, carotid-vertebrobasilar anastomosis; PPIA, persistent primitive proatlantal intersegmental artery; PPHA, persistent primitive hypoglossal artery; PPTA, persistent primitive trigeminal artery; CCA, common carotid artery; ICA, internal carotid artery; ACA, anterior cerebral artery; PCoA, posterior communicating artery; BA, basilar artery; AICA, anterior inferior cerebellar artery; SA, subclavian artery.