The Interaction between GSTT1, GSTM1, and GSTP1 Ile105Val Gene Polymorphisms and Environmental Risk Factors in Premalignant Gastric Lesions Risk
Table 1
The distribution of H. pylori infection, gastrotoxic medication, alcohol consumption, and smoking in the studied group.
Without endoscopic lesions ()
Mild or severe endoscopic lesions ()
value
Without premalignant lesions ()
With premalignant lesions ()
value
Age (mean ± SD)
65.64 ± 9.60
66.12 ± 7.88
0.656
65.06 ± 8.07
66.65 ± 9.85
0.149
≤60
45
23
0.480
38
30
0.485
>60
124
78
103
99
Sex
Female
95
44
0.059
73
66
0.920
Male
74
57
68
63
H. pylori infection
Negative
119
66
0.386
99
86
0.531
Positive
50
35
42
43
Gastrotoxic drugs
No
89
37
0.011
64
62
0.660
Yes
80
64
77
67
Smoking
Nonsmoker
157
90
0.280
136
111
0.002
Smoker
12
11
5
18
Alcohol
No
129
74
0.573
107
96
0.780
Yes
40
27
34
33
SD = standard deviation; presence of NSAIDs or antiplatelet therapy; 5 cigarettes/day including quitters during the past 5 years; onsumption of >10 units/week, obtained from Student’s -test for independent samples or Chi-square test.