Research Article

The Interaction between GSTT1, GSTM1, and GSTP1 Ile105Val Gene Polymorphisms and Environmental Risk Factors in Premalignant Gastric Lesions Risk

Table 1

The distribution of H. pylori infection, gastrotoxic medication, alcohol consumption, and smoking in the studied group.

Without endoscopic lesions ()Mild or severe endoscopic lesions () valueWithout premalignant lesions ()With premalignant lesions () value

Age (mean ± SD)65.64 ± 9.6066.12 ± 7.880.65665.06 ± 8.0766.65 ± 9.850.149
≤6045230.48038300.485
>601247810399
Sex
Female95440.05973660.920
Male74576863
H. pylori infection
Negative119660.38699860.531
Positive50354243
Gastrotoxic drugs
No89370.01164620.660
Yes80647767
Smoking
Nonsmoker157900.2801361110.002
Smoker1211518
Alcohol
No129740.573107960.780
Yes40273433

SD = standard deviation; presence of NSAIDs or antiplatelet therapy; 5 cigarettes/day including quitters during the past 5 years; onsumption of >10 units/week, obtained from Student’s -test for independent samples or Chi-square test.