Vitamin B-6, Independent of Homocysteine, Is a Significant Factor in Relation to Inflammatory Responses for Chronic Kidney Disease and Hemodialysis Patients
Table 2
Vitamin B-6 status and inflammatory markers in patients with chronic kidney disease or those receiving hemodialysis.
Stage CKD ()
Stage CKD ()
Hemodialysis ()
Vitamin B-6 status
Pyridoxal 5′-phosphate (nmol/L)
58.50 ± 8.52
84.31 ± 21.64
148.16 ± 26.76
<20 nmol/L (, %)
3, 8.82%
5, 14.71%
2, 2.94%
Pyridoxal (nmol/L)
15.85 ± 1.71
22.03 ± 4.82
30.08 ± 4.37
Homocysteine (μmol/L)
15.32 ± 0.65
28.22 ± 1.57
27.08 ± 1.03
≥14 μmol/L (, %)
22, 64.71%
34, 100%
68, 100%
Inflammatory markers
C-reactive protein (mg/L)
1.49 ± 0.52
3.86 ± 1.00
4.82 ± 1.17
Interleukin-1 (pg/mL)
1.28 ± 0.58
1.48 ± 0.18
1.18 ± 0.31
Interleukin-4 (pg/mL)
1.21 ± 0.30
0.97 ± 0.10
1.12 ± 0.17
Interleukin-6 (pg/mL)
10.38 ± 2.18
6.80 ± 0.97
6.36 ± 1.27
Interleukin-8 (pg/mL)
8.86 ± 1.31
7.73 ± 0.65
10.11 ± 1.59
Interleukin-10 (pg/mL)
13.76 ± 2.78
3.92 ± 0.61
6.35 ± 1.57
TNF- (pg/mL)
26.36 ± 8.35
26.58 ± 5.42
32.11 ± 13.50
Values are means ± standard error. TNF-, tumor necrosis factor-; Values with a different superscript letter are significantly different among groups; .
