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BioMed Research International
Volume 2017, Article ID 7514639, 7 pages
https://doi.org/10.1155/2017/7514639
Research Article

Jugular Venous Reflux Is Associated with Perihematomal Edema after Intracerebral Hemorrhage

1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
2China National Clinical Research Center for Neurological Diseases, Beijing 100050, China
3Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100050, China
4Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China
5Department of Diagnostic Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
6Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

Correspondence should be addressed to Jian Zhou; moc.361@yyttnaijuohz and Xingquan Zhao; moc.361.piv@qxz

Received 14 November 2016; Revised 1 April 2017; Accepted 11 May 2017; Published 11 June 2017

Academic Editor: Pasquale De Bonis

Copyright © 2017 Hao Feng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The purpose of this study was to determine whether jugular venous reflux (JVR) is associated with perihematomal edema (PHE) in individuals with intracerebral hemorrhage (ICH). Patients with spontaneous supratentorial ICH within 72 h of symptom onset were enrolled. Baseline brain computed tomography (CT) scan was performed, with a follow-up CT examination at 12 ± 3 days after onset. Jugular venous color Doppler ultrasound was performed at 12 ± 3 days after onset to examine the JVR status. A total of 65 patients with ICH were enrolled. In logistic regression analysis, absolute PHE volume was significantly associated with JVR (OR, 5.46; 95% CI, 1.04–28.63; ) and baseline hematoma volume (OR, 1.14; 95% CI, 1.03–1.26; ) within 72 h of onset. It was also correlated with JVR (OR, 15.32; 95% CI, 2.52–92.99; ) and baseline hematoma volume (OR, 1.14; 95% CI, 1.04–1.24; ) at 12 ± 3 days after onset. In a similar manner, relative PHE volume was significantly associated with JVR (OR, 14.85; 95% CI, 3.28–67.17; ) within 72 h of onset and at 12 ± 3 days after onset (OR, 5.87; 95% CI, 1.94–17.77; ). JVR is associated with both absolute and relative PHE volumes after ICH.