Modulation of Myostatin/Hepatocyte Growth Factor Balance by Different Hemodialysis Modalities
Table 1
Laboratory and dialysis parameters in patients at enrollment and at the end of each treatment period with different dialysis modalities.
Enrollment
BHD
HDF
BMI (kg/m2)
28.4 ± 4.7
28.8 ± 4.8
28.9 ± 5.1
0.5
Serum albumin (g/dl)
3.8 ± 0.3
3.7 ± 0.2
3.8 ± 0.2
0.5
C-RP (mg/dl)
0.47 (9.3–0.67)
0.6 (0.3–1)
0.45 (0.3–0.77)
0.3
Transferrin (mg/dl)
157.8 ± 15.1
167.7 ± 42.3
172.2 ± 32.1
0.2
Phosphate (mg/dl)
4.4 (3.8–5.7)
4.7 (4.3–5.3)
4.1 (3.9–4.7)
0.5
Calcium (mg/dl)
9 ± 0.3
9.3 ± 0.6
9.2 ± 0.5
0.6
PTH (pg/ml)
210 (149–359)
173.9 (106–599)
227 (156–361)
0.3
Lymphocyte count
1283 ± 673
1255 ± 588
1396 ± 567
0.5
BUN (mg/dl)
71.4 ± 8.6
80.2 ± 18.5
77.2 ± 13.1
0.4
spKT/V
1.46 ± 0.4
1.36 ± 0.25
1.42 ± 0.2
0.4
Predialysis myostatin (ng/ml)
6.0 ± 3.4
6.3 ± 4.1
4.3 ± 3.1
Number of patients
10
10
10
Predialysis HGF (pg/ml)
150.5 (44.2–681)
93 (42–231.8)
156.7 (88–201)
0.2
Number of patients
6
6
7
Data are expressed as mean SD or IQR (25–75). BHD = bicarbonate hemodialysis; HDF = online hemodiafiltration; C-RP = C-reactive protein; BUN = blood urea nitrogen; spKT/V = single-pool KT/V; HGF = hepatocyte growth factor. versus BHD.
