Research Article

Increase of Soluble RAGE in Cerebrospinal Fluid following Subarachnoid Haemorrhage

Table 1

Study group patients’ characteristic.

Male15 (56%)
Age (years)58.07 ± 15.8

Aneurysm location

Middle cerebral artery7 (26%)
Anterior communicating artery7 (26%)
Anterior cerebral artery4 (15%)
Basilar artery4 (15%)
Internal carotid artery3 (11%)
Posterior cerebral artery2 (7%)

Aneurysmal size (mm)5.08 ± 1.8
Cerebral infarction due to DCI on CT20 (74%)
Intracerebral haemorrhage on CT14 (52%)
Intraventricular blood on CT26 (96%)
Fisher CT score4 (4-4)
Modified Fisher CT score4 (2–4)
WFNS score on admission5 (3–5)
HH score on admission4 (4-5)
GCS on admission5 (4–10)

Post-SAH days 0–3Post-SAH days 5–7Post-SAH days 10–14

CRP level (mg/L)106.90 ± 88.9129.68 ± 96.875.09 ± 84.3
WBC count (106/mm3)13.81 ± 5,412.01 ± 5.014.35 ± 6.3
Hgb level (mg/dL)12.52 ± 1.712.10 ± 1.610.84 ± 1.2
Fibrinogen (mg/dL)415.61 ± 163.0617.63 ± 241.1600.33 ± 247.7
sRAGE (pg/mL)3.91 ± 4.04.24 ± 3.94.05 ± 3.8

Treatment outcome (according to GOS at 3 months)

Low disability (score of 5)5 (19%)
Moderate disability (score of 4)2 (7%)
Severe disability (score of 3)4 (15%)
Persistent vegetative state (score of 2)5 (19%)
Death (score of 1)11 (41%)