Review Article

Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder

Table 1

Classification of cutaneous manifestations of Crohn’s disease.

GroupType of lesions/diseases

(i) Direct extension from the bowel to the adjacent skin such as the perineal skin, stomal sites or lips [7](i) Fissures
(ii) Fistulas
(iii) Anal tags
(iv) Oral involvement

(ii) Dermatoses with a strong association with Crohn’s disease [2, 7, 8](i) Pyoderma gangrenosum
(ii) Erythema nodosum
(iii) Erythema multiforme
(iv) Epidermolysis bullosa acquisita
(v) Oral aphthae
(vi) Acrodermatitis enteropathica
(vii) Skin changes secondary to malabsorption
(viii) Psoriasis
(ix) Vitiligo
(x) Cutaneous polyarteritis nodosa

(iii) Skin lesions at sites noncontiguous to gastrointestinal tract [9](i) Metastatic Crohn’s disease